Yamabushitake (Lion’s Mane)
As of 2020, the only human study has used an oral dose of 1,000mg Yamabushitake (96% purity extract) thrice daily for a cumulative total of 3,000mg extract. While it is unknown if this is the optimal dose or not, it appeared to be effective.
Dose (E): 1 g, thrice per day.
Evidence scores: Anxiety (minor, 1), Cognitive decline. (minor, 1), Depression (minor, 1).