Adderall

Mr. Dependable

If there is a warped baffle-plate on the shield of your energy pile, Adderall will make it go away.

Adderall improves both clarity and motivation. (The meaning of clarity I am using is given here.)

Stimulants generally work by manipulating monoamine neurotransmission. Monoamines are a class of neurotransmitter relevant in reward, motivation, temperature regulation, and pain sensation, such as dopamine, norepinephrine, and serotonin.

  • Most stimulants inhibit the reuptake of dopamine and norepinephrine or stimulate their efflux. This results in increased activity of their pathways. This is accomplished by interfering with vesicular storage, activating TAAR1, and reversing the flow of monoamine transporters.
  • Other stimulants, like MDMA, alter serotonergic neurotransmission by antagonizing regulatory pre-synaptic auto receptors, blinding the pre-synaptic neuron to the actual amounts of material in the cleft.
  • Adrenergic stimulants, such as ephedrine, work by directly binding and activating the receptors that norepinephrine and epinephrine normally bind to.